The Midwest United States has incredible cities, beautiful national and state parks, and stunning beaches along the Great Lakes. So I’ve rounded up the top Midwest vacation rentals.

Midwest United States Travel Guide

Vacation homes let you explore the states of Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, and Wisconsin like a local.

Here are the best Midwest vacation rentals for your next getaway!

Beach Glamping

Jasonville, Indiana

5 guests · 1 bedroom · 3 beds · 1 bath

Picture yourself fishing, stargazing, and roasting marshmallows at this lakefront glamping site! You’ll have kayaks and paddleboards, a refrigerator, hot and cold running water in the tent, a gas grill, a fire pit, and a private sandy beach.

Lake Home Estate

Lake Geneva, Wisconsin

18 guests · 7 bedrooms · 13 beds · 4 baths

Highlights of this property are six indoor gathering places, a lakefront deck, a stunning rooftop deck, a private yard, a private beach, and a large private pier where you can dock two boats. This home has spectacular lake and sunset views, and you can walk to restaurants and bars.

Wide Open Spaces

Cottonwood Falls, Kansas

6 guests · 2 bedrooms · 2 beds · 2.5 baths

With nothing but prairie views for as far as the eye can see, the song Wide Open Spaces is the best way to describe this custom-built farmhouse. You’ll have huge windows, handmade walnut doors, cabinets, floors, and staircase, soaring ceilings, and a covered porch for enjoying the sea of grass that stretches to the horizon.

Luxury Highrise

Chicago, Illinois

8 guests · 2 bedrooms · 3 beds · 3 baths

If you want to feel like you’re in a luxury hotel, then this apartment is for you. There are direct views of Navy Pier from almost every window, and you’re centrally located for all of the city’s best attractions. You’ll also have access to the building’s state-of-the-art gym,  heated indoor lap pool, sundeck, fire pits, grilling stations, and private cabanas.

Butler, Ohio

8 guests · 2 bedrooms · 3 beds · 2 baths

This remote cabin is the perfect getaway for any season. You’ll be surrounded by five acres of pine forest that “whispers” in the wind. The home has a hot tub, patio, and fire pit that are perfect for stargazing, a gas fireplace, an oversized tub, stainless steel appliances, and lots of rustic charm.

THE DUGOUT

St. Louis, Missouri

16 guests · 4 bedrooms · 18 beds · 2 baths

This 2,400 sq ft baseball-themed property in St. Louis can actually sleep up to 32 people, so it’s perfect for reunions, friends groups, visiting sports teams, and large family gatherings. Plus, you’ll only be a short walk from Busch Stadium and Gateway Arch National Park.

The Mushroom House

Charlevoix, Michigan

14 guests · 6 bedrooms · 10 beds · 5.5 baths

This famous three-story thatch house makes for an iconic vacation (imagine this home on your Instagram feed)! The home is spacious and close to the beach. Because of how well-known this house is, don’t be surprised when people stop to take pictures from the street.

Discover all of the Best Vacation Homes in Michigan

Year-Round Treehouse

Burtrum, Minnesota

9 guests · 2 bedrooms · 5 beds · 1 bath

To get to this 18-feet-off-the-ground treehouse, you’ll walk over a thirty-foot covered bridge. The home sits on a ridge overlooking Rock Lake, surrounded by 500 acres of state land. You’ll have central heat and air, a wrap-around porch, hot tub, and easy access to trails for walking, snowshoeing, and cross-country skiing.

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This article about the best Midwest vacation rentals is not a sponsored post, and the thoughts and opinions expressed in this post are entirely my own. Some of the links in this post about the best Midwest vacation rentals are affiliate links, and, at no cost to you, I may earn a small commission.